Home / Isis Launches Phase I/II Clinical Trial of ISIS-DMPKrx to Treat DM1

Isis Launches Phase I/II Clinical Trial of ISIS-DMPKrx to Treat DM1

Isis Pharmaceuticals, Inc. (NASDAQ: ISIS) has initiated a Phase I/II trial for ISIS-DMPKrx in patients affected by myotonic dystrophy type 1 (DM1).

This study is designed to evaluate the safety and tolerability of multiple doses of an investigational compound, ISIS-DMPKrx, in adult patients with DM1. ISIS-DMPKrx is designed to reduce the production of toxic dystrophia myotonic-protein kinase (DMPK) RNA in cells, including muscle cells, for the treatment of DM1.

Questions? Visit the MDF Clinical Trials Resource Center. Up-to-date information regarding trial sites, recruitment and trial site contact information is posted on www.clinicaltrials.gov.

[Update: Results from the Phase I/II Trial study were announced on January 5, 2017: Ionis Pharmaceuticals Reports DMPKRx Phase 1/2 Trial Results. Ionis Pharmaceuticals and Biogen also released a letter to the DM community in January 2017.]

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