A new DM1 mouse model, with postnatal expression of expanded CUG repeat RNA in the brain, implicates reduced MBNL1 and MBNL2 in the staging of pathological and functional changes.
Registration is open! Register now for the 2017 MDF Annual Conference
MDF is pleased to announce the launch of a new program, MDF DM Days. These special one-day free events will be held in three locations across the U.S. in 2017, bringing together clinicians, researchers and MDF community members to share information and resources.
The currently active NHLBI initiative, NHLBI Clinical Trial Pilot Studies (R34), provides funding for up to 3 years/$450,000 total direct costs to support studies sufficient to the design of interventional clinical trials in their mission.
Epigenetic modifications upstream of an expanded DMPK allele may underlie the maternal bias in the inheritance of CDM.