Patterns:

• Pregnancy can exacerbate DM2. A few reports indicate that pregnancy can exacerbate or unmask the onset of myotonia and cause increased pain in DM2. More research is needed to confirm these observations.

• The effects of DM2 on both smooth and striated muscle can complicate pregnancy, labor and delivery.

Diagnosis:

• Discuss the following tests with your doctor:

  • Preimplantation genetic diagnosis to determine whether the embryo is affected or prenatal genetic diagnosis to determine if the fetus has the DM2 genetic expansion.

  • Reproductive and fertility/infertility history inculding personal and family history.

Treatment:

• Family planning.

• Refer to genetic counseling, family planning and other specialists as indicated.

• Prenatal and preimplantation genetic diagnosis can allow for termination of the pregnancy or selective implantation of unaffected embryos.