December 2019 Research News

• Lower Extremity Motor Control in DM1
• Toward a Cardiac Biomarker for DM1?
• Metformin Use for Diabetes May Reduce Cancer Risk in DM1
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

November 2019 Research News

• Tissue-Specific Sensitivities to DM1 Repeat Expansion
• Toward a Cardiac Biomarker for DM1?
• Patient Experiences with Cannabinoids in DM
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

October 2019 Research News

• Understanding Falls in DM Patients
• Assay Development to Identify Small Molecule Drugs for DM1
• Gait Impairment in DM1
• Methods in Molecular Biology: DM Methodology
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

September 2019 Research News

• Welcome to Myotonic!
• Evolving Strategies Using Oligonucleotides for DM1
• Toward Functional Outcome Measures for Clinical Trials in DM1
• Small Molecule Candidates Targeting Primary Disease Mechanisms in DM
• Internuclear Transfer of Toxic RNA in DM1?
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

August 2019 Research News

• Molecular Genetics Model of CDM
• Status Report: Genome Editing in DM1
• How to Talk About A DM1 Diagnosis
• Upstream Methylation Impacts Muscle and Respiratory Function in DM1
• Agenda Updated for Myotonic CNS Outcome Measures Development Workshop
• 2020 Request for Fellowship Applications Currently Open
• Updated Professional Track at the 2019 Myotonic Annual Conference
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

July 2019 Research News

• Myotonic Leadership Transition
• Sizing Expanded DMPK Repeats
• The DM-Scope Registry Model
• A Genetic Modifier of DM1
• A Tighter Relationship Between CTG Repeat Length and DM1 Phenotype?
• Agenda Updated for Myotonic CNS Outcomes Measures Development Workshop
• 2020 Request for Fellowship Applications Currently Open
• Updated Professional Track at the 2019 Myotonic Annual Conference
• Career Development: John Cleary, Ph.D., Joins the RNA Institute, University of Albany
• Career Development: John Lueck, Ph.D., Joins the University of Rochester
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

June 2019 Research News

• Agenda Announced for Myotonic CNS Outcomes Measures Development Workshop
• Submit a Poster to the 2019 Myotonic Annual Conference!
• 2020 Request for Fellowship Applications Currently Open
• Register for the 2019 Myotonic Annual Conference!
• Annual Nationwide Children’s Hospital/OSU Myology Course
• Career Development: Congratulations Dr. Gene Yeo! Finalist of the 2019 Blavatnik National Awards for Young Scientists and winner of the Xconomy "Big Idea" Award
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

May 2019 Research News

• Targeting DM1 with a Multivalent Ligand
• What is the Actual Progenitor Allele Length in Any Given DM1 Patient?
• Dysregulation of Circular RNAs in DM1
• CNS and Myotonic Dystrophy: Scientific Premise and Potential Targets Workshop
• Register for the 2019 Myotonic Annual Conference!
• Registration Open Now: IDMC-12, June 2019
• Annual Nationwide Children’s Hospital/OSU Myology Course
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

April 2019 Research News

• Linking DM Molecular Events to Insulin Resistance and Muscle Atrophy
• Targeting Toxic RNA in DM1 with a Small Molecule Drug
• Potential Involvement of RNAi Mechanisms in DM1
• CNS and Myotonic Dystrophy: Scientific Premise and Potential Targets Workshop
• Annual Nationwide Children’s Hospital/OSU Myology Course
• Pharma/Biotech Updates
• Registration Open Now: IDMC-12, June 2019
• Register for the 2019 Myotonic Annual Conference!
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

March 2019 Research News

• Sleep and Disordered Breathing in DM2
• Potential for Genome Editing in Neuromuscular Disease
• New Perspective on Respiratory Involvement in DM1
• Decline in Daily and Social Activities in DM1
• Clinical Care Recommendations for DM1 Now in Italian
• Registration Open Now: IDMC-12, June 2019
• Save the Date for the 2019 Myotonic Annual Conference!
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

February 2019 Research News

• Characterizing Pediatric DM1
• Health-Related Quality of Life in DM1
• Publication of Christopher Project Report
• Cognitive and Adaptive Development in Congenital/Childhood DM1
• Registration Open Now: IDMC-12, June 2019
• Save the Date for the 2019 Myotonic Annual Conference!
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

January 2019 Research News

• Non-Invasive Molecular Measures in a DM1 Mouse
• High Speed / Throughput Sizing of Expanded Repeats
• New Release: Research Funding Opportunity from the 2019 PRMRP
• Announcing 2019 Myotonic Fellows
• Save the Date: CNS Outcome Measures Workshop
• SAVE THE DATE: IDMC-12, June 2019
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

December 2018 Research News

• Lessons Learned: Targeting RNA as a Therapeutic Strategy
• A Novel Genome Editing Strategy for DM1
• Drug Development Informed with TACT
• SAVE THE DATE: IDMC-12, June 2019
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

November 2018 Research News

• Challenges in Assessing the CNS in DM1
• Corticospinal Tract Involvement in DM1
• Mechanism of Myogenic Defects in CDM
• AMO Pharma Press Release Provides Its Analysis of Phase 2 Study Results
• SAVE THE DATE: IDMC-12, June 2019
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

October 2018 Research News

• Non-Invasive Biomarkers for DM1
• Review: What Have We Learned About RAN Translation?
• Scn5a and Cardiac Conduction in DM
• Myotonic Dystrophy Approved for Important 2019 Defense Funding Program!
• SAVE THE DATE: IDMC-12, June 2019
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

September 2018 Research News

• DM1 Care Recommendations Published
• Status: Clinical Outcome Measures for DM2
• Human iPSC-Derived Neurons for DM2
• Furamidine Mechanism of Action in DM1
• SAVE THE DATE: IDMC-12, June 2019
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

August 2018 Research News

• MDF Releases RFA for DM1 Genome Editing Research
• NIAMS Releases New Funding Opportunities
• Modifiers of MBNL-Dependent Splicing in Health and Disease
• Fuchs’ Corneal Dystrophy in DM1 Patients Lacking the Fuchs’ Mutation
• DM1 Phenotype Modified by Repeat Interruptions
• Join Academic and Industry Colleagues at the 2018 MDF Annual Conference
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

July 2018 Research News

• Therapeutic Gene Modulation: Targeting Muscleblind's Regulation by miRs
• OPTIMISTIC View of DM1
• NAS Releases Report on Patient Involvement in Research
• NIH Evaluates Wellstone Muscular Dystrophy Research Centers Program
• Richard T. Moxley, III, MD Tribute Program
• Join Academic and Industry Colleagues at the 2018 MDF Annual Conference
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

June 2018 Research News

• PRMRP - A New Funding Source for DM Research
• Senators Play Key Role in Getting DM Access to New Federal Research Funds
• Join Academic and Industry Colleagues at the 2018 MDF Annual Conference
• Mechanisms of Muscle Wasting in DM1
• Similar Molecular Mechanisms, but Divergent Phenotypes in DM1 and DM2 - Why?
• Important New Review Articles on DM
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

May 2018 Research News

• Join Academic and Industry Colleagues at the 2018 MDF Annual Conference
• Update: Research Funding Opportunity from the PRMRP
• New Release: NINDS Preclinical Translational Research Funding
• Quantifying Mutant mRNA in DM1 and DM2
• Microsatellite Expansions Selective Trigger Intron Retention
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

April 2018 Research News

• New Release: Research Funding Opportunity from the PRMRP
• Regulation of MBNL1 Localization and Function in the CNS
• Using iPSC-Derived Cardiomyocytes to Understand DM1
• NHGRI Genomic Medicine Research Initiative
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

March 2018 Research News

• Predictors of DM1 Patient Survival
• Determinants of Respiratory Function in DM1
• DM and the Canadian Neuromuscular Disease Registry
• Thanks Dr. John Porter, Welcome Dr. Lisa Ackermann!
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

February 2018 Research News

• Comorbidity of Childhood DM1 and Autism?
• Imaging Neurocircuitry Changes in DM2 Mice
• The Future of Genetic Therapies
• Understanding the Functional Domains of MBNL
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

January 2018 Research News

• MDF Receives $1M Grant to Launch Gene Editing Program for DM1
• New Biotech Company Announces Major Funding for DM Therapy Development
• MDF Funds Expansion of the DMCRN
• NIH Releases 2018 Funding Opportunities
• MDF and Wyck Award $300K in New Research Fellowships
• Toward 'Reponsive' Outcome Measures for DM1
• GSK3β As A Drug Development Target For DM1
• A Tool for Evaluating Drugs Targeting MBNL
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

December 2017 Research News

• MDF Successfully Advocates for DM Inclusion in Pentagon Research Funding Program
• Search for Prognostic Biomarkers for DM Cardiac Conduction Abnormalities
• Skin Cancer Risks in DM1
• NIH to Release RFA to Re-Compete Rare Disease Clinical Research Network
• NIH Will Fund Biomarker Validation for Neurological Diseases
• NINDS Emphasizes Basic Research
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

November 2017 Research News

• Interaction of Age and Gender in DM2
• IL-6 Myokine Signaling in CDM
• Finding the Right CRISPR Targets for DM
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

October 2017 Research News

• RAN Translation In DM2
• The Origin of Insulin Resistance in DM
• What We Do (and Don’t) Know About Cognitive Function in DM1
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

September 2017 Research News

• Understanding DM1 Patient Perceptions About Their Disease
• Current Status of Brain Imaging in DM1
• Risk of GI Manifestations in DM1 and DM2
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

August 2017 Research News

• Gene Editing Repurposed Toward Toxic RNA
• Understanding and Measuring Fatigue in DM1
• Molecular Events Underlying Congenital DM
• Currently Accepting Applications: Ph.D. Trainee and Postdoctoral Research Fellowships in DM
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

July 2017 Research News

• New Drosophila Models for DM1 and DM2
• Preclinical Data Behind the Ionis Trial Published
• DM1 Genotype and Cardiac Phenotype
• MDF at 2017 BIO International Convention
• Keep Us Updated!
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

June 2017 Research News

• The Path We’re On: Many Challenges, but Ultimately a Drug
• Do We Treat DM as a Brain Disease?
• Book Your Hotel Room Now for IDMC-11
• DM Highlights at the 2017 AAN Annual Meeting
• Myotonic Dystrophy PFDD Meeting Report Submitted to FDA
• NIH Update: Advice for Grantseekers
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

May 2017 Research News

• Reduced MBNL1 Precedes Structural and Functional Changes in the DM1 Mouse Brain
• Patient-Reported Data to Guide Care and a Cure for DM
• MDF Publishes First Article in Scientific Journal
• IDMC-11 Abstract Deadline Approaching
• NIH Update—NINDS Program Project Grants (P01)
• New and Important Review Articles on DM
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

April 2017 Research News

• Epigenetics Underlying the Parent of Origin Effect in CDM
• A Biomarker for Cardiac Dysfunction in DM1?
• Registration Now Open for IDMC-11
• MDF Reports on NIH and NHLBI Funding Opportunities​
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

March 2017 Research News

• Gene Editing for DM
• FDA: How to Talk with Us About INDs
• Changes in NINDS Postdoctoral Training Initiatives
• Adequate Rationale to Launch Clinical Trials
• Last Chance to Give Feedback About the DM Research News
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

February 2017 Research News

• Treating Sleep Disorders in DM1
• AMPK/mTORC1 Signaling as a Therapeutic Target for DM1
• Is NINR a Source for DM Funding?
• Improving Clinical Trials in Myotonic Dystrophy
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

January 2017 Research News

• Ionis Pharmaceuticals Reports on DMPKRx Phase 1/2 Clinical Trial
• Cognitive Changes in Adult DM1: An Acceleration of Normal Aging?
• Wyck Foundation and MDF Announce Grant Awards
• Toward Effective Biomarkers for DM
• Upcoming Conferences & Meetings
• Funding Opportunities (Subscribe to DM Research News for details)
• Recent DM Research Publications (Subscribe to DM Research News for details)

December 2016 Research News

• MDF Staff Meets with NIAMS and NINDS
• Using PROMS to Evaluate Potential Therapies
• Research Fellow Profile: Łukasz Sznajder
• MDF to Move Care and a Cure Agenda Forward at January Planning Offsite
• MDF Requesting Details on Studies & Trials
• Funding Opportunities (Subscribe to DM Research News for details)
• Upcoming Conferences & Meetings
• Recent DM Research Publications (Subscribe to DM Research News for details)

November 2016 Research News

• IDMC-11 and MDF Annual Conference in San Francisco in Fall 2017
• NIH Now Requires the Posting of Failed Trial Data
• Research Fellow Profile: Dr. Laura Renna
• Funding Opportunities (Subscribe to Newsletter for details)
• Upcoming Conferences & Meetings

October 2016 Research News

• The Curious Dilemma of Classifying DM1
• Qualifying a Biomarker for DM
• Videos from 2016 MDF Annual Conference Available Now
• Research Fellow Profile: Dr. Ginny Morriss
• Funding Opportunities (Subscribe to Newsletter for details)
• Upcoming Conferences & Meetings

September 2016 Research News

• Kidney Dysfunction Is a Risk in DM1: How to Assess It
• Gender-Related Cancer Risk in DM1
• DMPK Silencing Unlikely to be Factor in ASO Treatment of DM1
• Professionals Track and MDF Annual Conference a Success
• UK Sitcom Features DM Patient
• Funding Opportunities (Subscribe to Newsletter for details)
• Upcoming Conferences & Meetings

August 2016 Research News

• New Study on DM1 Brain Changes 
• Last Call to Register for the 2016 MDF Annual Conference
• New Grants Awarded
• AMO Pharma Initiates Phase II Clinical Trial for DM
• Research Fellow Profile: Dr. Benjamin Gallais
• Funding Opportunities (see Newsletter for details)
• Upcoming Conferences & Meetings

July 2016 Research News

• New Grants Awarded
• Understanding the Genetic Causes of DM: Evaluation of Role of Other Gene Variants 
• MDF Active at the 2016 BIO International Convention 
• It's Not Too Late: Registration is Open for the 2016 MDF Annual Conference
• ENMC Meeting Report
• Funding Opportunities (see Newsletter for details)
• Upcoming Conferences & Meetings

June 2016 Research News

• New! Professional Track at the 2016 MDF Annual Conference 
• Miami Summit: Finalization of DM Clinical Care Recommendations
• Current Grant Oppurtunities 
• MDF Fellow Advances Stem Cell Research Targeting Muscle Regeneration 
• Recent Publications
• Funding Opportunities (see Newsletter for details)
• Upcoming Conferences & Meetings

May 2016 Research News

• Ionis Pharmaceuticals Reports on Studies
• Call for Posters at 2016 MDF Annual Conference
• Gender Matters in DM1
• Rare Chemistry: Matt Disney Recognized by NIH for Advancing Small Molecule Therapeutics for DM
• Recent Publications
• Funding Opportunities (see Newsletter for details)
• Upcoming Conferences & Meetings

April 2016 Research News

• MDF Welcomes John as Interim Chief Science Officer
• Early Bird Registration Now Open: MDF 2016 Annual Conference
• Interview with Research Fellow Melissa Dixon, Ph.D.
• Announcement: New Research Funding Opportunities
• The Genetics of DM1 Repeat Size
• Recent Publications
• Funding Opportunities (see Newsletter for details)
• Upcoming Conferences & Meetings

March 2016 Research News

• Dr. Charles Thornton Wins Presitigious Javits Award
• Wyck Foundation & MDF Award Drug Screening Grant to UFL-Sanofi Collaboration
• Research Fellow Profile: Dr. Ian DeVolder
• Industry Corner: Cloud Pharmaceuticals
• Exclusive Sessions for Professionals at the 2016 MDF Annual Conference (see Newsletter for details)
• Recent Publications
• Funding Opportunities (see Newsletter for details)
• Upcoming Conferences & Meetings

February 2016 Research News

• Study Examines the Impact of DM on Pregnancy
• Multi-Disciplinary Approach Needed for Congenital and Childhood DM Care
• MDF Launches Research Participation Campaign for Rare Disease Day
• Recent Publications
• Funding Opportunities (see Newsletter for details)
• Upcoming Conferences and Meetings

January 2016 Research News

• International Alliance Formed for Care and a Cure (see Newsletter for details)
• Six DM Research Fellowships Awarded
• MDF 3.0: Accelerating Drug Development
• MDF SAC Member Profile: Kathie Bishop, Ph.D.
• Isis Pharmaceuticals Becomes Ionis Pharmaceuticals
• Careers: Tetsuo Ashizawa, M.D., Moves to Houston Methodist
• FDA Boosts Patient Focused Drug Development
• FDA Rejects BioMarin's Duchenne Treatment

December 2015 Research News

• MDF SAC Member Profile: Dr. Laura Ranum
• Common Symptoms of DM2 and Their Impact on Daily Living
• 2015 Muscular Dystrophy Action Plan Will Guide Federal Funding Priorities
• Recent Publications
• Funding Opportunities (see Newsletter for details)
• Upcoming Conferences & Meetings

November 2015 Research News

• MDF SAC Member Profile: Tom Cooper, MD
• Benefit/Risk Study Results: Reduce Muscle Weakness
• DM Prevalence Study Phase I Announcement
• Recent Publications
• Funding Opportunities (see Newsletter for details)
• Upcoming Conferences & Meetings

October 2015 Research News

• Experts Participate in DM Regulatory Workshop
• New Recommendations for Patient Groups & Trial Sponsors
• Recent Publications
• Funding Opportunities (see Newsletter for details)
• Upcoming Conferences & Meetings

September 2015 Research News

• FDA Draft Guidance for Drug Development on Rare Diseases
• MDF Fellow Profile: Dr. Melissa Hinman
• Industry Corner: Cytoo (see Newsletter for details)
• Recent Publications
• Upcoming Conferences & Meetings
• Funding Opportunities (see Newsletter for details)

August 2015 Research News

• Therapy Development for Myotonic Dystrophy
• Congress Acts to Spur Research, Drug Development
• Upcoming Conferences & Meetings
• Funding Opportunities (see Newsletter for details)
• Recent Publications (see Newsletter for details)
• Career Developments (see Newsletter for details)